Disease Progression and Clinical Outcomes in Telomere Biology Disordersby Dr....
Individuals with telomere biology disorders (TBDs) like dyskeratosis congenita (DC) are confronted with numerous health issues during their lifetime. TBDs do not always look the same – some people may...
View ArticleStudying the Functional Interaction Between Compound Heterozygous TERT...
My laboratory first started work on telomerase, the molecule that elongates telomeres, more than 20 years ago; at the time, we were interested in the fundamental biochemistry behind this intriguing...
View ArticleCharacterization of Telomere Maintenance in Tumor Models of Dyskeratosis...
Our amazing 2020 Team Telomere Million Dollar Bike Ride Grant Awardee was Dr. Judy Wong! Her project, “Characterization of Telomere Maintenance in Tumor Models of Dyskeratosis Congenita”, worked to...
View ArticleEditing TINF2 as a Potential Therapeutic Approach to Restore Telomere Length...
Despite their frequency and severe impact on children in the TBD community, mutations in the gene TINF2 remain some of the least understood causes of telomere biology disorders (TBDs). Significantly,...
View ArticlePatient Engagement and Involvement in Rare Disease Research: Spotlighting...
Team Telomere’s patient registry was recently featured in Nature, the world’s leading multidisciplinary science journal! Megan O’Boyle is the parent of a 22-year-old daughter with a rare...
View ArticlePre-malignant Clonal Evolution in Telomere Biology Disordersby Dr. Daria...
We are excited to share an update on our research project, “Pre-malignant Clonal Evolution in Telomere Biology Disorders,” supported by the Team Telomere Million Dollar Bike Ride Grant. Telomere...
View ArticlePharmacologic Rescue of Telomere Defects in Dyskeratosis Congenitaby Dr. Brad...
Telomere disorders including dyskeratosis congenita (DC) manifest in stem cell failure in highly proliferative tissues such as the skin, blood, and gut, as well as fibrosis in organs including lung and...
View ArticleThymidine Nucleotide Metabolism Controls Human Telomere Lengthby Will...
Our lab focuses on understanding what controls telomere length from a molecular level, with the hope that this knowledge will help us develop new therapies to treat telomere related diseases. This...
View ArticleThe Experience and Management of Medical Uncertainty in Telomere Biology...
The Telomere Biology Disorder community sends major congratulations to Dr. Emily Pearce for defending her dissertation and earning her PhD! Dr. Pearce’s thesis was titled “The Experience and Management...
View ArticleDr. Blanche Alter receives prestigious Wallace H. Coulter Award for Lifetime...
Dr. Blanche Alter, MD, MPH received the prestigious Wallace H. Coulter Award for Lifetime Achievement in Hematology at the 65th American Society of Hematology Annual Meeting in December 2023! Dr....
View ArticleDisease Progression and Clinical Outcomes in Telomere Biology Disordersby Dr....
Individuals with telomere biology disorders (TBDs) like dyskeratosis congenita (DC) are confronted with numerous health issues during their lifetime. TBDs do not always look the same – some people may...
View ArticleStudying the Functional Interaction Between Compound Heterozygous TERT...
My laboratory first started work on telomerase, the molecule that elongates telomeres, more than 20 years ago; at the time, we were interested in the fundamental biochemistry behind this intriguing...
View ArticleCharacterization of Telomere Maintenance in Tumor Models of Dyskeratosis...
Our amazing 2020 Team Telomere Million Dollar Bike Ride Grant Awardee was Dr. Judy Wong! Her project, “Characterization of Telomere Maintenance in Tumor Models of Dyskeratosis Congenita”, worked to...
View ArticleEditing TINF2 as a Potential Therapeutic Approach to Restore Telomere Length...
Despite their frequency and severe impact on children in the TBD community, mutations in the gene TINF2 remain some of the least understood causes of telomere biology disorders (TBDs). Significantly,...
View Article